To provide immunoglobulin-binding proteins having improved stability to alkali.SOLUTION: The problem is solved by an immunoglobulin-binding protein containing at least domain C of Staphylococcus bacteria-derived protein A, but having an amino acid residue at a specific position replaced with another specific amino acid residue, in the domain, and having improved stability to alkali.SELECTED DRAWING: None

You do not currently have access to this content.