To provide cancer treatment methods that are highly safe, enhance the therapeutic effect of cancer, and can prevent cancer metastasis and recurrence, and to provide monitoring methods for determining the therapeutic effect of PPAR-gamma agonist in cancer patients.SOLUTION: Provided is a cancer treatment method that comprises a first analysis step of analyzing the peripheral blood circulation tumor cells (CTC) of a mammalian subject, a step of administering an effective amount of PPAR-gamma agonist to a subject in need of treatment based on the results of the above analysis, and a second analysis step of analyzing the peripheral blood circulating tumor cells (CTC) of the subject after administration of the PPAR-gamma agonist.SELECTED DRAWING: Figure 1

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