Objectives This study evaluates the intake, tolerability and effect of aged garlic extract (AGE) on cardiovascular markers (blood pressure, body composition, glycemic and lipid parameters), stool consistency and its relationship with dietary factors. Casuistry and Methods This is a randomized, double-blind, placebo-controlled clinical trial that included 19 hypertensive volunteers. Participants were randomly treated daily with 1.2 g of AGE (1.2 mg of s-allylcysteine) or placebo for 12 weeks. Mixed model analysis was used to detect possible pressure, dietary and body changes, which were assessed every 4 weeks. At these times the consistency of the stool was also evaluated using the Bristol scale. The biological markers, collected before and after the experimental period (fasting glucose, glycated hemoglobin, total cholesterol, low density lipoprotein, high density lipoprotein, very low-density lipoprotein, triglycerides, and non-HDL cholesterol) were analyzed using parametric tests. Results Only the AGE group showed significant reductions in systolic levels at week 4...

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