Disclosed is a cosmetic case having a refill structure including: a container body having one opened side and formed with an elevation spiral groove; an outer cap rotatably coupled to the container body and formed with an elevation straight groove; an elevation mechanism elevated in the container body while being rotated with the outer cap and formed with an elevation protrusion; a content container accommodated inside the container body to store contents; a discharging mechanism installed in the content container to discharge the contents; an inner cap coupled to one side of the content container and elevated with the elevation mechanism; and an operation button connected to the discharging mechanism to discharge the contents, wherein the elevation mechanism and the inner cap are formed with a fastening protrusion and a fastening groove and formed with a refill guide groove and a refill guide protrusion, respectively.

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