To provide a manipulation system capable of stably and automatically collecting a minute object into a container and a driving method for the manipulation system.SOLUTION: A manipulation system comprises: a container in which a minute object is accommodated; a sample stage on which the container is mounted; a collection pipet for collecting the minute object; a drive control unit for controlling the sample stage and the collection pipet; a calculation unit for calculating an approximate expression of a plane which approximates a plurality of inspection points measured on a bottom surface of the container; and a storage unit for storing the approximate expression.SELECTED DRAWING: Figure 11

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