The present invention relates to a composition for skin whitening, and more particularly, to a topical preparation, cosmetic or health functional food composition for skin whitening, which includes carvedilol as an active ingredient. The composition of the present invention, which includes carvedilol as an active ingredient, exhibits a whitening effect by suppressing the expression of a melanin synthesis gene by reducing MITF through inhibition of CREB phosphorylation in normal human melanocytes (NHMs), and gradually weakens cell tyrosinase activity over time, lowering the risk of a side effect of pigmentation. Therefore, the composition is expected to be effectively used in development of materials for cosmetics and health functional food and related industries in safe and effective ways.

Keywords
FOOD ADDITIVES FOOD ENRICHMENT FOODS FUNCTIONAL FOODS INGREDIENTS ORGANIC COMPOUNDS SKIN
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