The probiotic E. Coli Nissle 1917 (EcN) plays an important role in regulating the microbial components of the gut and preventing inflammation of the gastrointestinal tract. Currently, the long-term use of antibiotics for the treatment of lethal white diarrhea in chicks caused by Salmonella has led to increased morbidity and mutation rates. Therefore, we want to use EcN as an antibiotic alternative as an alternative approach to prevent Salmonella-induced white diarrhea in chickens. To date, there are no reports of EcN being used for the prevention and control of Salmonella pullorum (S. pullorum) in chickens. In vitro, pretreatment with EcN significantly decreased the cellular invasion of S. pullorum CVCC533 in a chicken fibroblast (DF-1) cell model. Then, 0-day-old egg-laying chickens were orally inoculated with EcN at a dose of 109 CFU/100 μL at either Day 1 (EcN1) or both Day 1 and Day 4 (EcN2)....
Protective effects of E. coli Nissle 1917 on chickens infected with Salmonella pullorum.
Yanlong Jiang, College of Animal Medicine, Jilin Provincial Engineering Research Center of Animal Probiotics, Jilin Provincial Key Laboratory of Animal Microecology and Healthy Breeding, Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun, 130118, China. E-mail email@example.com
Chao Sun, Xingyun Gao, Ming Sun, Zhannan Wang, Ying Wang, Xiaohan Zhao, Futing Jia, Tongyu Zhang, Chongbo Ge, Xiao Zhang, Menglei Zhang, Guilian Yang, Jianzhong Wang, Haibin Huang, Chunwei Shi, Wentao Yang, Xin Cao, Nan Wang, Yan Zeng, Chunfeng Wang, Yanlong Jiang; Protective effects of E. coli Nissle 1917 on chickens infected with Salmonella pullorum.. IFIS Food and Health Sciences Database 2023; doi:
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