Provided are an electroporation method, an electroporation circuit, and a DC high-voltage power supply circuit that use the electroporation circuit that reduces a load on an element and prevents failure of the element. An electroporation method using an electroporation circuit (1), the electroporation circuit comprising at least two or more capacitors (C1-cm), each of which is connected in series, a plurality of time constant changing units (2), a switch (S11-Sun), And a resistance R 11 c-R MN connected in series to the switch. Figure 1

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