The purpose of the present invention is to provide a method for determining which of new subtype classifications dependent on the characteristics of tumors, particularly tumors in which the ErbB receptor signaling system is involved in clinical characteristics, using new biomarkers. A method of treating a tumor in a patient, the method comprising: Obtaining data on an expression level of an EGFR gene in the tumor of the patient and data including an expression level of at least one gene selected from the group consisting of RBB2, ERBB3 and ERBB4, or the sum of the expression levels of two or more genes, based on the ratio of the expression levels of one gene selected from the group consisting of ERBB3 and ERBB4, or the sum of the expression levels of two or more genes. Fig. 8

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