To provide an angiopoietin-like factor 2(Angptl2) inhibitor.SOLUTION: An Angptl2 inhibitor has a compound having a specific chemical structure represented by formula (I) or a pharmaceutically acceptable salt thereof. There are also provided a cosmetic product, quasi drug, pharmaceutical, or food composition containing the inhibitor. [R-Rindependently represent H or the like].SELECTED DRAWING: Figure 4

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