Introduction. A large body of evidence suggests that propolis exerts antioxidant, anti-inflammatory, and antimicrobial activities, mostly ascribed to its polyphenol content. Growing evidence suggests that propolis could modulate gut microbiota exerting a positive impact on several pathological conditions. The aim of this study was to determine the in vitro impact of a poplar-type propolis extract with a standardized polyphenol content, on the composition and functionality of gut microbiota obtained from fecal material of five different donors (healthy adults, and healthy, obese, celiac, and food allergic children). Methods. The standardized polyphenol mixture was submitted to a simulated in vitro digestion-fermentation process, designed to mimic natural digestion in the human oral, gastric, and intestinal chambers. The antioxidant profile of propolis before and after the digestion-fermentation process was determined. 16 S rRNA amplicon next-generation sequencing (NGS) was used to test the effects on the gut microbiota of propolis extract. The profile of the...
Evaluating the effects of a standardized polyphenol mixture extracted from poplar-type propolis on healthy and diseased human gut microbiota.
J. A. Rufian-Henares, Departamento de Nutricion y Bromatologia, Instituto de Nutricion y Tecnologia de los Alimentos, Centro de Investigacion Biomedica (CIBM), Universidad de Granada, Granada, Spain. E-mail firstname.lastname@example.org
Garzarella, E. U., Navajas-Porras, B., Perez-Burillo, S., Ullah, H., Esposito, C., Santarcangelo, C., Hinojosa-Nogueira, D., Pastoriza, S., Zaccaria, V., Jianbo Xiao, Rufian-Henares, J. A., Daglia, M.; Evaluating the effects of a standardized polyphenol mixture extracted from poplar-type propolis on healthy and diseased human gut microbiota.. IFIS Food and Health Sciences Database 2023; doi:
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