Plant-based protein products, either as a protein supplement or food ingredient, have gained increasing consumer attention and interest owing to their "organic" green nature and health benefits. Particularly, pea (Pisum sativum) has recently emerged as an important source of plant-based protein. The health benefits of pea protein could be attributed to at least two aspects: the peptides from hydrolyzed/digested protein that possess biological activities; and their interaction with human gut microbiota, which is a fundamental element in understanding the pathophysiology of diseases such as obesity, type-2 diabetes, and cardiovascular diseases. Therefore, we herein discuss recent advances in the production of health-beneficial pea biopeptides with antioxidant, antimicrobial, antihypertensive, and antidiabetic activities, while also dissertating their potential to influence gut microbiota. All rights reserved, Elsevier.

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