Sialyllactoses (SL) are an abundant component of human milk. There have been many studies on the biological effects of SL in humans. SL can be produced using an economical method of enzyme synthesis. Although the European Food Safety Authority has published the human safety and appropriate intake dose of 6â€²-SL sodium salt as a novel food, it has suggested that the appropriate dose for particular medical purposes be judged on a case-by-case basis. Also, as revealed in the same report, there are no data on toxicity when 6â€²-SL is used in human intervention. However, clinical studies have only confirmed the safety of 3â€²-SL for therapeutic intervention in humans, and the safety for therapeutic use of 6â€²-SL, which is more abundant than 3â€²-SL in human milk, has not been confirmed. In this study, to determine the safety of 6â€²-SL use in humans, participants were randomly assigned to the placebo (maltodextrin) and...
Randomized, triple-blind, placebo-controlled study to evaluate the safety of 6′-sialyllactose in healthy adults.
Sang-Yeol Yong, Department of Rehabilitation Medicine, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju-si, Gangwon-do, 26426, South Korea. E-mail email@example.com
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Ji Hyun Kim, Sang-Yeol Yong, Sung Hoon Kim, Ahreum Baek, Tae-Hwa Go, Dae-Ryong Kang; Randomized, triple-blind, placebo-controlled study to evaluate the safety of 6′-sialyllactose in healthy adults.. IFIS Food and Health Sciences Database 2022; doi:
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