Problem to be solved. To find out a novel substance having higher proliferation promoting activity for a stem cell, and provide a proliferation promoter of a stem cell, a proliferation promoting method of a stem cell, and a cosmetic, a medicine, a quasi drug or a food/drink product containing the proliferation promoter of a stem cell. Solution. A proliferation promoter of a stem cell which contains furfural derivative as an active ingredient. Namely, the present invention is usable as a preparation method of a stem cell and/or proliferation promoter of a stem cell in regenerative medicine or regenerative cosmetic.

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