Nano-selenium particles (SeNPs) are considered to have high biological activity and low toxicity, but their stability need to be improved. Konjac glucomannan (KGM) was introduced as a stabilizer for the preparation of SeNPs via ascorbic acid (AA)-sodium selenite (Na2SeO3) redox system in this study, the influence of reaction conditions on the formation of KGM-SeNPs was estimated and the preparation parameters were optimized via orthogonal experiment. It is found that KGM concentration and Se4 + concentration are the two most important parameters that affect the particle size and morphology of KGM-SeNPs, beside of the agglomeration promoted by higher temperature. The optimal product possessed spherical particles with a particle size of 50-150 nm, the selenium content in lyophilized supernatant and lyophilized precipitate were 38.17% and 19.19%, respectively, and infrared spectroscopy analysis showed KGM-SeNPs were mainly compounded by intermolecular electrostatic interaction. KGM-SeNPs exhibited inhibitory effects on Staphylococcus aureus...
Nano-selenium stablilized by Konjac Glucommannan and its biological activity in vitro.
Xiang Li, Hubei Engineering Research Center of Selenium Food Nutrition and Health Intelligent Technology, Hubei Minzu University, 39 Xueyuan Road, Enshi City, Hubei Province, 445000, China. E-mail email@example.com
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Jingya Song, Jingjing Zhou, Xiang Li, Peilin Li, Guozheng Tian, Chi Zhang, Dazhai Zhou; Nano-selenium stablilized by Konjac Glucommannan and its biological activity in vitro.. IFIS Food and Health Sciences Database 2022; doi:
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