Antineoplastic potential in human breast adenocarcinoma, cervical cancer cells and cytotoxicity in non-tumoral cells was assessed using Pecan nut (Carya illinoinensis L.) oil. The global yield of Pecan oil extracted by Goldfish method (GD) ranged from 23.53% (1 h) to 47.73% (6 h) whereas than by pressurized ethanol extraction (PEE) and pressurized propane extraction (PPE) it was obtained a maximum global yield of 32.43% and 54.79%, during 40min, respectively. Chromatographic profiles indicated the presence of palmitic, stearic, oleic (main compound), linoleic, linolenic, caproic and arachidic acids. Cervical squamous cancer cells (SiHa), breast cancer cells (MCF-7) and non-tumoral immortalized human keratinocytes (HaCat) were treated with different concentrations of oils by 24 h and cell viability was measured by MTT assay. The extracts obtained from Goldfish method showed the best results for the treatment of cervical cancer cells (IC50 of 16.46μg mL-1 and selectivity index of 0.75). All rights...

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