Abnormal cross-talk between the intestinal microbiota of host animals and their immunity is evidently associated with an increase in the prevalence of allergy, and some selected probiotics have been found to play a role in pertinent mechanisms. Herein we evaluated the anti-allergic effects and mechanisms of two newly identified strains isolated from infant feces, namely Bifidobacterium breve 207-1 (207-1) and Lacticaseibacillus paracasei 207-27 (207-27), in ovalbumin-sensitized mice. We found that 207-27 showed stronger anti-allergic effects than 207-1 and even Lacticaseibacillus rhamnosus GG, which could be attributed to enhanced systemic and intestinal mucosal immunity, restored intestinal microbiome, and enriched Lactobacillaceae. In addition, 207-1 markedly enhanced splenic cytokine levels and partially restore microbial dysbiosis in allergic mice. To summarize, 207-27 and 207-1 could characteristically influence host immunity and intestinal microbiota in a strain-dependent manner. We believe that 207-27 is a promising probiotic strain considering its beneficial effects on the host. All rights...
Anti-allergic effects of two potential probiotic strains isolated from infant feces in China.
Fang He, Department of Nutrition and Food Hygiene, West China School of Public Health and West China Fourth Hospital, Sichuan University, 610041 Chengdu, Sichuan, China. E-mail firstname.lastname@example.org
- Views Icon Views
- Share Icon Share
- Search Site
Huijing Liang, Yujie Zhang, Zhonghua Miao, Ruyue Cheng, Fengling Jiang, Xiaolei Ze, Xi Shen, Fang He; Anti-allergic effects of two potential probiotic strains isolated from infant feces in China.. IFIS Food and Health Sciences Database 2022; doi:
Download citation file: