Problem to be solved. To provide a chronic renal disease progression inhibitor having excellent progression inhibitory action of a chronic renal disease. Solution. A chronic renal disease progression inhibitor containing a bacterial cell of a lactic acid bacterium that belong to genus Enterococcus and at least one kind selected from the group consisting of bacterial cell components thereof, in which the lactic acid bacterium is Enterococcus faecalis NF-1011 strain (FERM BP-10902), the bacterial cell is a dead bacterial cell, and at least one kind selected from the group consisting of lytic enzyme of the lactic acid bacterium and the bacterial cell being a heated product, and bacterial cell components thereof.
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