Hops (Humulus lupulus L.), a major constituent of beer, is composed of resins, polyphenols, hop essential oils, various proteins, cellulose, and water. Hops and hop components are well-known for their antimicrobial effects on bacterial growth. Hop components contribute to human health, and numerous studies have shown hops as potent antimicrobial, anti-inflammatory, and anticancer agents. Most health benefits are derived from three main hop components: polyphenols, bitter acids, and essential oil. The effect of hop components on oral health cannot be ignored, considering their role in systemic health. Hop components may have potential uses in treating oral diseases, such as dental caries, periodontal diseases, oral lichen planus, oral candidiasis, and others. However, few studies have focused on the effects of hops on oral health. This review discusses the beneficial effects of hop components on systemic health and potential applications in oral diseases. All rights reserved, Elsevier.

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