Presenteeism is a major issue faced by workplaces around the world. While nutritional education has been well studied for its resolution, few studies have reported its effectiveness. Promoting worker health is also a major issue. To solve these problems, we developed a novel dietary intervention using nutritionally balanced meals, "COMpletely Balanced meal (COMB meal)". Two single-arm open-label trials were conducted; employees at two major companies consumed these meals every weekday for four weeks, replacing breakfast and lunch. The comprehensive score of the Work Limitation Questionnaire-Japanese version was significantly improved in one trial and it was significantly improved in the presenteeism subgroup of both trials. Body weight, Body Mass Index, waist circumference, and visceral fat decreased and the number of defecations increased significantly in both trials. Serious adverse effects were not observed. This study is the first to show multiple effects of dietary interventions, including improvement in presenteeism. All rights reserved,...

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