The anti-proliferative/pro-oxidant efficacy of green pea, soybean, radish, Red Rambo radish, and rocket microgreens, cultivated under either fluorescent lighting (predominant spectral peaks in green and orange) or combination light-emitting diode (LED, predominant spectral peak in blue) was investigated using Ewing sarcoma lines, RD-ES and A673, respectively. All aqueous microgreen extracts significantly reduced cell proliferation (cancer prevention effect) to varying extents in two-dimensional sarcoma cell cultures. The effect of the polyphenol fraction in the aqueous food matrix was unrelated to total polyphenol content, which differed between species and light treatment. Only Pisum sativum (LED-grown) extracts exercised anti-proliferative and pro-apoptotic effects in both three-dimensional RD-ES and A673 spheroids (early tumor progression prevention), without cytotoxic effects on healthy L929 fibroblasts. A similar anti-tumor effect of Red Rambo radish (LED and fluorescent-grown) was evident only in the RD-ES spheroids. Aside from the promising anti-tumor potential of the polyphenol fraction of green pea microgreens, the...
Microgreens: functional food with antiproliferative cancer properties influenced by light.
Department of Agricultural and Food Sciences, University of Bologna, Viale Fanin, 44-40127 Bologna, Italy. Tel. +39-05-1209-6673. E-mail email@example.com
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Truzzi, F., Whittaker, A., Roncuzzi, C., Saltari, A., Levesque, M. P., Dinelli, G.; Microgreens: functional food with antiproliferative cancer properties influenced by light.. IFIS Food and Health Sciences Database 2022; doi:
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