The occurrence and development of breast cancer are closely related to dietary factors, especially dietary patterns. This study was to investigate the effects of dietary patterns on the process of tumor metastasis by in vivo circulating tumor cell (CTC) capture strategy and monitoring changes of CTC numbers in breast tumor mice model. Meanwhile, the effects of different dietary patterns on the development of lung metastases of breast cancer and the volume and weight of carcinoma in situ were investigated. In this study, the increase in the number of CTCs was significantly promoted by dietary patterns such as high-salt diet, high-sugar diet, and high-fat diet, while it was delayed by ketogenic diet, low-fat diet, low-protein diet, diet restriction, and Mediterranean diet. These results indicated that the in vivo capture and detection of CTCs provides a convenient method for real-time cancer metastasis monitoring, and through in-depth study of the effects of different...
Evaluation of the effects of different dietary patterns on breast cancer: monitoring circulating tumor cells.
Hongyan Zhang, Shandong Provincial Key Laboratory of Animal Resistance Biology, Institute of Biomedical Sciences, Key Laboratory of Food Nutrition and Safety of Shandong Normal University, College of Life Science, Shandong Normal University, Jinan 250014, China. Tel. +86-0531-86180745. E-mail firstname.lastname@example.org
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Xiuxiu Wang, Xiaoyu Liu, Zhenzhen Jia, Yilun Zhang, Shuo Wang, Hongyan Zhang; Evaluation of the effects of different dietary patterns on breast cancer: monitoring circulating tumor cells.. IFIS Food and Health Sciences Database 2022; doi:
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