Immunosuppression occurs in response to a variety of external antigens. However, various immune cells and cytokines can activate the immune system. In this study, it was found that fermented deer velvet (FD) and fermented Eleutherococcus senticosus (FE) extract (FDE) mixtures regulated the immunity of animals that underwent induced immunosuppression through forced swimming exercise (FSE). Seven mouse treatment groups were included in the experiment: normal controls, FSE controls, positive controls (FSE+red ginseng 300 mg/kg body weight), FD200 (FSE+FD 200 mg/kg body weight), FE200 (FSE+FE 200 mg/kg body weight), FDE50 (FSE+FDE 50 mg/kg body weight), and FDE200 (FSE+FDE 200 mg/kg body weight). Oral intake of experimental and control substances lasted for 2 weeks. Oral FDE intake increased cell counts for major histocompatibility complex (MHC) I, MHC II, CD4(+) T cells, and CD8(+) T cells compared with controls. Moreover, FDE increased Th1 (interleukin [IL]-2 and interferon gamma) cytokine proliferation, T cell...
Deer velvet and Eleutherococcus senticosus mixture regulated immune function in C57BL/6N mice with immunosuppression induced by forced swimming.
Jeongmin Lee, Department of Medical Nutrition, Kyung Hee University, Yongin 446-701, Korea. E-mail firstname.lastname@example.org
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Soo-Jeung Park, Minhee Lee, Jeong-Moon Yun, Dakyung Kim, Dong Hwan Oh, Jinkyung Kim, Myeongkuk Shim, Hee-Jin Oh, Jeongmin Lee; Deer velvet and Eleutherococcus senticosus mixture regulated immune function in C57BL/6N mice with immunosuppression induced by forced swimming.. IFIS Food and Health Sciences Database 2022; doi:
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