The effect of the fermented beverage of Rose rugosa cv. Plena and Lycium barbarum L. on the auricle microcirculation in rats.

Objective. To investigate the effect of the sample "fermented beverage of Rose rugosa cv. Plena and Lycium barbarum L." on the auricle microcirculation in female rats, Methods. The experimental animals were randomly divided into four groups according to their body weight: normal control group, low-, medium-and high-dose group of fermented beverages. The normal control group was given deionized water by intragastric administration. Laser Doppler blood flow meter was used to observe the perfusion unit (PU) of rat auricle microcirculation by the effect of the beverage in normal state and microcirculation disturbance caused by high molecular dextran. Results. Under the normal conditions, the blood flow perfusion and velocity of microcirculation in rats were significantly increased after 14 days of intragastric administration (P<0.05), and the function of enhancing blood flow perfusion was maintained thereafter until 30 days. Meanwhile, in the model of microcirculatory disturbance, the microvascular contraction effect of SD rats induced...