This study evaluates the effects of probiotics and synbiotics on the performance, immune responses, and intestinal morphology, and the expression of immunity-related genes of broiler chicks challenged with Salmonellatyphimurium. Three hundred and sixty broiler chicks were divided into six groups, including broiler chicks challenged and non-challenged with S.typhimurium and fed with probiotic, synbiotic, and basal diet without additive. Growth performance (food intake, daily gain, feed conversion ratio, and mortality), immune responses (antibody titer against sheep red blood cells, immunoglobulins G and M), intestinal morphology, lactic acid bacteria population, and the expression of immunity-related genes (interferon-γ, interleukins 6 and 12, and tumor necrosis factor-α) were investigated. The administration of S.typhimurium decreased growth performance (P=0.0001), immune responses (P=0.0001), intestinal morphology (P=0.0001), lactic acid bacteria population (P=0.0001), and the expression of immunity-related genes (P=0.0001) of broiler chickens. However, broiler...

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