Bacteriophage composition.

This composition for lysis of Staphylococcus aureus or this composition for prevention or therapy of diseases caused by Staphylococcus aureus contains as active ingredients: at least one bacteriophage selected from the group consisting of the bacteriophage identified by Accession No. NITE BP-693 and the bacteriophage identified by Accession No. NITE BP-694; and an endolysin that is at least one protein selected from the group consisting of (a) a protein having the amino acid sequence of SEQ ID NO: 1; (b) proteins having an amino acid sequence having 80% or more identity to the amino acid sequence of SEQ ID NO: 1; and (c) proteins having an amino acid sequence obtained by providing one or more amino acid substitutions, deletions, additions, and/or insertions to the amino acid sequence of SEQ ID NO: 1.